Natrol Msm/Glucosamine Creme 4 oz - Natural Eucalyptus Fragrance Topical Creme Formula MSM with Glucosamine Creme is a topical formula combines the nourishment of MSM and Glucosamine with the deep-heating action of capsicum and a host of synergistic herbs to bring fast relief for overworked joints and muscles. MSM with Glucosamine Creme is a topical application that penetrates deeply to relieve pain, inflammation, and tightness associated with arthritis.